Wen-Hsing Cheng

Wen-Hsing Cheng

Professor
Graduate Coordinator

Office: 208 Herzer Bldg.

Mailing Address:

Box 9805
945 Stone Blvd.
Mississippi State, MS 39762

Education:

  • Ph.D., Cornell University
  • M.S., Cornell University
  • B.S., National Taiwan University

Research/Extension Areas:

  • Molecular nutrition
  • Aging and age-related disorders
  • Obesity and energy metabolism

Courses Taught:

  • FNH 4123/6123: Nutrition and Chronic Disease
  • FNH 8253: Nutrition and Food Science Research
  • FNH 8990: Molecular Nutrition

Society Memberships:

  • American Society for Nutrition

Publications

2019
Shao, Z., Z. Zhang, H. Fan, X. Wang, H. Wu, L. Zhang, W.-H. Cheng, J. Zhu. 2019. Selenoprotein T Promotes Proliferation and G1-to-S Transition in SK-N-SH Cells: Implications in Parkinson's Disease. Journal of Nutrition 149:2110-2119. Download

2019
Zhang, X., R. Liu, W.-H. Cheng, J. Zhu. 2019. Prioritized brain selenium retention and selenoprotein expression: Nutritional insights into Parkinson's disease. Mechanisms of Ageing and Development 180:89-96. Download

2018
Dhowlaghar, N., P. D. Abeysundara, R. Nannapaneni, M. W. Schilling, S. Chang, W.-H. Cheng, C. S. Sharma. 2018. Biofilm formation by Salmonella spp. in catfish mucus extract under industrial conditions. Food Microbiology 70:172-180. Download

2018
Dhowlaghar, N., Q. Shen, P. Abeysundara, A. Jadhav, R. Nannapaneni, M. W. Schilling, W.-H. Cheng, C. S. Sharma. 2018. Differences in survival of heat stress adapted cells of Listeria monocytogenes EGD (Bug600) in disinfectants and in essential oils. The Journal of the Mississippi Academy of Sciences 63:333-343.

2018
Lu, H.-Y., H. Zeng, L. Zhang, J. M. Porres, W.-H. Cheng. 2018. Fecal fermentation products of common bean-derived fiber inhibit C/EBPα and PPARγ expression and lipid accumulation but stimulate PPARδ and UCP2 expression in the adipogenesis of 3T3-L1 cells. The Journal of Nutritional Biochemistry 60:9-15. Download

2018
Zhang, L., H. Zeng, W.-H. Cheng. 2018. Beneficial and paradoxical roles of selenium at nutritional levels of intake in healthspan and longevity. Free Radical Biology and Medicine 127:3-13. Download

2018
Zhang, L., J. H. Zhu, X. Zhang, W.-H. Cheng. 2018. The thioredoxin-like family of selenoproteins: Implications in aging and age-related degeneration. Biological Trace Element Research 188:189-195. Download

2017
Cao, L., L. Zhang, H. Zeng, R. Wu, T-L. Wu, W.-H. Cheng. 2017. Analyses of selenotranscriptomes and selenium concentrations in response to dietary selenium deficiency and age reveal common and distinct patterns by tissue and sex in telomere dysfunctional mice. Journal of Nutrition 147(10):1858-1866. Download

2017
Lu, H.-Y., W.-H. Cheng. 2017. Selenoproteins and Epigenetic Regulation in Mammals. In: Patel V., Preedy V. (eds) Handbook of Nutrition, Diet, and Epigenetics. Springer, Cham. Download

2017
Zeng, H., D. Taussig, W.-H. Cheng, L. Johnson, R. Hakkak. 2017. Butyrate inhibits cancerous HCT116 colon cell proliferation but to a lesser extent in noncancerous NCM460 colon cells. Nutrients 9(1):25. Download

2016
Cheng, W.-H., X. Lei. 2016. Selenium: Basic Nutritional Aspects. In: J.F. Collins (eds) Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals. Elsevier. Download

2016
Lai, J., X. Zhang, F. Liu, R. Yang, S. Li, L. Zhu, M. Zou, W.-H. Cheng, J. Zhu. 2016. Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2. Oncotarget 7:43731-43745. Download

2016
Lei, X. G., J.-H. Zhu, W.-H. Cheng, Y. Bao, Y.-S. Ho, A. Reddi, A. Holmgren, E. Arnér. 2016. Paradoxical roles of antioxidant enzymes: Basic mechanisms and health implications. Physiological Reviews 96(1):307-364. Download

2016
Marioli, C., M. Balzarini, F. Aguate, N. Grosso, D. Soldini, H. Zeng, W.-H. Cheng, M. J. Martinez. 2016. Climatic thresholds for concentrations of minerals and heavy metals in Argentinean soybeans. Agronomy Journal 108(2):532-539. Download

2016
Wu, R., l. Cao, E. Mattson, K. Witwer, J. Cao, H. Zeng, X. He, G. Combs Jr., W.-H. Cheng. 2016. Opposing impacts on healthspan and longevity by limiting dietary selenium in telomere dysfunctional mice. Aging Cell 16(1):125-135. Download

2016
Zhang, X., L. Zhang, J.-H. Zhu, W.-H. Cheng. 2016. Nuclear selenoproteins and genome maintenance. IUBMB Life 68(1):5-12. Download

2016
Zhang, X., Y. Wang, J. Zhu, X. Liu, H. You, M. Gong, M. Zou, W.-H. Cheng, J. Zhu. 2016. N-acetylcysteine negatively regulates Notch3 and its malignant signaling. Oncotarget 7: 30855-30866. Download

2016
Zhang, X., Y. Ye, H. Zhu, S. Sun, J. Zheng, H. Fan, H. Wu, S. Chen, W.-H. Cheng, J. Zhu. 2016. Selenotranscriptomic analyses identify signature selenoproteins in brain regions in a mouse model of Parkinson's disease. PLoS ONE 11(9):e0163372. Download

2016
Zhao, C., H. Zeng, R. Wu, W.-H. Cheng. 2016. Loss of selenium-binding protein 1 decreases sensitivity to clastogens and intracellular selenium content in HeLa cells. PLoS ONE 11(7): e0163372. Download

2013
Rocourt, C., M. Wu, B.P.C. Chen, W.-H. Cheng. 2013. The catalytic subunit of DNA-dependent protein kinase is downstream of ATM and feeds forward oxidative stress in selenium-induced senescence response. Journal of Nutritional Biochemistry 24: 781-787. Download

2013
Rocourt, C., W.-H. Cheng. 2013. Selenium supranutrition: Are the potential benefits of chemoprevention outweighted by the promotion of diabetes and insulin resistance? Nutrients 5:1349-1365. Download

2012
Holmstrong, A., R.T.Y. Wu, H. Zeng, K.Y. Lei, W.-H. Cheng. 2012. Nutritional and supranutritional levels of selenate differentially suppress prostate tumor growth in adult but not young nude mice. Journal of Nutritional Biochemistry 23:1086-1091. Download

2011
Wu, M., R.T.Y. Wu, T.T.Y. Wang, W.-H. Cheng. 2011. Role for p53 in selenium-induced senescence. Journal of Agriculture and Food Chemistry 59:11882-11887. Download

2011
Zhang, S., Y. Luo, H. Zeng, Q. Wang, F. Tian, J. Song, W.-H. Cheng. 2011. Encapsulation of selenium in chitosan nanoparticles improves selenium availability and protects cells from selenium-induced DNA damage response. Journal of Nutritional Biochemistry 22:1137-1142. Download

2010
Qi, Y., N.W. Schoene, F. Lartey, W.-H. Cheng. 2010. Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells. Journal of Biological Chemistry 285: 33010-33017. Download

2010
Wu, M., M. Kang, N.W. Schoene, W.-H. Cheng. 2010. Selenium compounds activate early barriers of tumorigenesis. Journal of Biological Chemistry 285:12055-12062. Download

2008
Cheng, W.-H., D. Muftic, M. Muftuoglu, L. Dawut, C. Morris, T. Helleday, Y. Shiloh, V.A. Bohr. 2008. WRN is required for ATM activation and the S-Phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks. Molecular Biology of the Cell 19(9):3923-3933. Download

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